In context of infected characters:

- Does the disease effect physical abilities (strength, healing capabilities, ect.)?
- Does the disease limit magic users from using their powers?
- If it does limit their magic, how much of it?
- Is the scarcity of food resources going to be sudden or are characters going to start noticing that there is less food all the way up to the event start date?
- Can people still hunt or is animal game going to be scarce as well?
- Blood packs are available, yes, but can blood-drinking characters still feed off of other people or is that a no-go so that scarcity is still a thing?
- How does the infection spread since the only listened symptoms are fever and whatever characteristic goes with the chosen disease? Is it touch contact, airbourne, ect?
- Will the disease be affecting wildlife and thus make hunting impossible since you could contract the disease from the animal?
- Are corpses contagious since this is spread through some kind of contact?

I'll probably think of more but XD here's some.