Well, I mean, there's a lot of different stuff going on that could potentially change the way he reacts - fundamentally he's most likely to just be like "asshole what are you doing get out of the house" without really touching the Lisa Lisa issue in general.

...on the other hand if he does something explicitly to Holly then obviously that's going to change Jotaro's approach, and by extension what it is he's most pissed about, so. :|a